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A Review on Background of Xenotransplantation, Xenosis, Advantages/Disadvantages and Ethics of Xenotransplantation

Samra Ashfaq, Nida Tabassum Khan*

Department of Biotechnology, Faculty of Life Sciences & Informatics, Balochistan University of Information Technology, Engineering and Management Sciences, Balochistan

*Corresponding author: Nida Tabassum Khan, Department of Biotechnology, Faculty of Life Sciences & Informatics, Balochistan University of Information Technology, Engineering and Management Sciences, Takatu Campus, Airport Road, Quetta, Balochistan; Email: [email protected]

Received Date: March 22, 2024

Publication Date: April 12, 2024

Citation: Khan NT, et al. (2024). A Review on Background of Xenotransplantation, Xenosis, Advantages/Disadvantages and Ethics of Xenotransplantation. Dermis. 4(2):14.

Copyright: Khan NT, et al. © (2024).

ABSTRACT

The recent unavailability of donor organs for transplantation in patients with life-threatening organ failure is demonstrated by the situation with kidney transplantation. The expectation of many people is associated with organ transplant globally. In 1907 A. Carrel proposed that a large supply of tissues and organs makes it possible to treat people which are ill early before they reach to severe condition by using animals as organ donor. So there is no need for patients to wait for the organs to transplant and this transfer provides the permanent alternates of organs. Clinical cross-species xenotransplantation has a long history going back to blood transfusions across species in the 17th century. When normal microbes that are produced by animals act as foreign substance for human against which they generate an immune response and this pathogen possess harmful effects on human so this phenomenon is described as xenosis. By the advantages of xenotransplantation the dangers that are associated with infections overcomes. Although increased danger of infections in transplantation is caused by many aspects. There are some ethical concerns linking to probable human receivers of animal organs and also for animals as bases of organs for human beings.

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